Multimolig-M and silicon are essential fertilisers that enhance crop growth and yield. Silicon provides structural and protective benefits, while Multimolig-M supplies crucial micronutrients for metabolic functions, improving yield and quality. This study aims to evaluate the effects of silicon and Multimolig-M on the morphological characteristics, growth, and yield of the VTNA6 rice variety in Nghe An Province, Central Vietnam. The experiments were conducted using a randomised complete block design (RCBD) with three replications. Three levels of Multimolig-M (M₁: 360 ml/ha; M₂: 420 ml/ha; M₃: 480 ml/ha) and silicon (Si₁: 120 kg/ha; Si₂: 160 kg/ha; Si₃: 200 kg/ha) were applied. The results indicated significant improvements in flag leaf length, flag leaf width, panicle length, plant height, number of leaves, number of tillers, and number of effective tillers applying fertilisers. The treatment combination of 420 ml/ha Multimolig-M and 200 kg/ha silicon (M₂Si₃) produced the highest theoretical yield of 10.32 tons/ha and a net yield of 7.93 tons/ha, suggesting a synergistic effect of the two fertilisers. These findings highlight the positive impact of combining 420 ml/ha Multimolig-M with 200 kg/ha silicon on optimising yield and growth characteristics for VTNA6 rice, making it a recommended approach for enhancing rice productivity under local conditions in Nghe An.