e-ISSN 2231-8542
ISSN 1511-3701
Mulyati, Lasmini Syariatin and Fajar Sofyantoro
Pertanika Journal of Tropical Agricultural Science, Pre-Press
DOI: https://doi.org/10.47836/pjtas.47.1.10
Keywords: Chlorella vulgaris, hematological profile, rats, stress
Published: 2024-02-19
Stress has been associated with various diseases and physiological disruptions. Chlorella vulgaris is known for its antioxidant properties. This study examined the effects of C. vulgaris on the hematological profile of stress-induced Wistar rats. Stress significantly impacted various hematological parameters, including erythrocyte count, hemoglobin concentration, hematocrit levels, white blood cell count, and platelet count. The supplementation of cultivated C. vulgaris effectively restored erythrocyte count and suppressed elevated lymphocyte levels, while commercially available C. vulgaris and amitriptyline drugs had no significant effects on these parameters. Stress caused smaller-sized erythrocytes but did not significantly affect mean corpuscular volume. Both amitriptyline and C. vulgaris restored platelet levels, while mean platelet volume remained unaffected. Overall, C. vulgaris showed promise as a therapeutic intervention for countering stress-induced inhibition of erythropoiesis and restoring erythrocyte count, but more research is needed to understand the underlying mechanisms and develop effective strategies for managing stress-related changes in hematological parameters.
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e-ISSN 2231-8534
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