Security is a major concern for the communication sector. The technique presented in this paper provides a novel security key generation mechanism. The proposed technique aims to generate a security key using the biological characteristics of the human body and the mathematically generated pseudo random sequences, thus producing different keys for different individuals. The final key is produced through the fusion of deoxyribonucleic acid (DNA) sequence of 1024 characters and Bernoulli Random Number Generator sequence of 256 bits. The performance of produced keys is evaluated using National Institute of Standards and Technology (NIST) tests and uniqueness is verified through avalanche test.