e-ISSN 2231-8542
ISSN 1511-3701

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Dose Optimisation of 18F-Flurodeoxyglucose for Whole Body PET Oncology Examination in CDNI of UPM

Hishar, H., Salasiah, M., Fathinul Fikri, A. S. and Nordin, A. J.

Pertanika Journal of Tropical Agricultural Science, Volume 23, Issue 2, July 2015

Keywords: 18F-FDG, PET/CT, PET image quality, optimum dose, administered dose/body weight (kg), MIP

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A shift to administration of optimal dose of 18F-FDG between 4 and 5 MBq/kg from the current practice of higher doses potentially yields a reasonable-to-excellent PET image. For this purpose, whole-body MIP images of 32 patients (23 men, 9 women, age 51.9 ± 13.7 years), administered with 18F-FDG(activity 5.3 ± 0.5 MBq/kg, 45 minutes uptake time) for whole-body PET/CT examinations, were evaluated. Image quality was assessed visually by two radiologists using a three-point scoring scale: poor, reasonable and excellent. The interobserver agreement revealed a kappa value higher than 0.7. Therefore, the utilisation of 18F-FDG dose between 4 and 5MBq/kg is considered an optimum dose for whole-body PET/CT examination.

ISSN 1511-3701

e-ISSN 2231-8542

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