e-ISSN 2231-8542
ISSN 1511-3701

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Potential of 3'-Fluoro-3' Deoxythymidine as a Cellular Proliferation Marker in PET Oncology Examination

Hishar, H., R. Price, Fathinul Fikri, A. S., Eddie Lau, W. F., Assunta, C. and A. J. Nordin

Pertanika Journal of Tropical Agricultural Science, Volume 24, Issue 1, January 2016

Keywords: 18F-FLT, 18F-FDG, Positron Emission Tomography (PET), cellular proliferation

Published on: 28 Dec 2015

Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker forenhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3'-fluoro-3'deoxythymidine (18F-FLT), has been developed as a biomarker for cell proliferation. In this review, the potential of 18F-FLT as a biomarker for cancer imaging is discussed.

ISSN 1511-3701

e-ISSN 2231-8542

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