e-ISSN 2231-8542
ISSN 1511-3701

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Silicon Nanowire Interface Circuit for DNA Detection

Kamilu Iman Usman, Mohd Nizar Hamidon, Siti Fatimah Abd Rahman and Guan Ling Sim

Pertanika Journal of Tropical Agricultural Science, Volume 25, Issue S, February 2017

Keywords: Silicon nanowire, nanoelectronics, interface circuit, DNA detection

Published on: 09 May 2017

Detection and quantification of DNA is critical to many areas of life sciences and health care, from disease diagnosis to drug screening. The transduction of DNA through electrochemical methods have a fast response rate and with a conductometric device like the silicon nanowire which can be fabricated to have a similar diameter of the DNA molecule being targeted, detection is real-time. Critical to this is the interfacing of a current-source and an amplifier capable of achieving a maximum of 10 pico ampere input bias. In this project, we fabricated a silicon nanowire using the top down approach and built a circuit that can mimic the output signal as low as 12 nA and achieved a gain of 1 million to be interfaced with the nanowire for real-time DNA detection.

ISSN 1511-3701

e-ISSN 2231-8542

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