F.B.H. AHMAD and J.M. BRUCE
Pertanika Journal of Tropical Agricultural Science, Volume 7, Issue 2, August 1984
Keywords: 2.5-Dimethoxybenzaldehyde; bromination reaction.
Published on:
Bromination of 2,5-dimethoxybenzaldehyde (1) gives 4-bromo-2,5-dimethoxy-benzaldehyde (2) and not 6-bromo-2f5-dimethoxybenzaldehyde (3) as previously reported by Rubenstein (1925). It appears that the conjugation of the carbonyl group with the ortho methoxy group (as structure 4) does not control the orientation of this bromination reaction. A series of reactions which confirm the structure of the bromination product will be discussed.
ISSN 1511-3701
e-ISSN 2231-8542