Hishar, H., R. Price, Fathinul Fikri, A. S., Eddie Lau, W. F., Assunta, C. and A. J. Nordin
Pertanika Journal of Science & Technology, Volume 24, Issue 1, January 2016
Keywords: 18F-FLT, 18F-FDG, Positron Emission Tomography (PET), cellular proliferation
Published on: 28 Dec 2015
Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker forenhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3'-fluoro-3'deoxythymidine (18F-FLT), has been developed as a biomarker for cell proliferation. In this review, the potential of 18F-FLT as a biomarker for cancer imaging is discussed.
ISSN 0128-7680
e-ISSN 2231-8526