The role of working women has evolved because of changes in economic conditions and social demands in recent years. Many married women have become economic contributors to their families. However, they struggle with pressure on handling their jobs and maintaining family integrity. Can married female employees’ job performance be enhanced by work-life balance or others? This study aimed to examine the effects of work-life balance and affective commitment on married female employees’ job performance in Indonesia. A structural equation modeling-partial least square was used to analyze the responses gathered via a questionnaire survey from married female employees working in the banking sector in Indonesia. Results showed that work-life balance significantly affected job performance. Affective commitment mediated the relationship between work-life balance and job performance. This study revealed that work-life balance not only directly affected job performance but also indirectly influenced it through affective commitment. This study also discussed the implications for married female employees’ balancing of family and work.